An anthology of five loosely connected stories dealing with a variety of very different women in dealing with their own life problems. The first story 'This is Dr. Keener' features Glenn Close as a doctor looking after her invalid mother who comes to realize that her own life is passing her by. The second story 'Fantasies About Rebecca' features Holly Hunter as a wealthy bank manager who doesn't realize that her own life is a sham in dealing with an unplanned pregnancy, a workaholic boyfriend, and an observant street woman who knows more about Rebecca than she herself does. The third, 'Someone For Rose' features Kathy Baker as a single mother who debates with herself over starting a romance with a dwarf who moves into the house across her street. The fourth, 'Goodnight Lilly, Goodnight Christine' features Calista Flockhart as Christine, a tarot reader who struggles with increasing grief and depression while taking care of her lesbian lover Lilly who's dying from cancer. The fifth, 'Love Waits for Kathy' features Amy Brenneman as a police detective who examines her loneliness after her blind sister Carol begins dating while Kathy is on a case of investigating the suicide of an old school friend who was just as lonely as she.