| movie | The Hunger Games: Sunrise on the Reaping (2026)As Drusilla Sickle | (Not seen) |
| tv | All's Fair (2025)As Dina Standish(9 episodes) | (Not seen) |
| movie | Netflix Tudum 2025 (2025) | (Not seen) |
| movie | Wake Up Dead Man: A Knives Out Mystery (2025)As Martha Delacroix | (Not seen) |
| movie | Back in Action (2025)As Ginny | (Not seen) |
| movie | Super/Man: The Christopher Reeve Story (2024)As Self | (Not seen) |
| movie | Brothers (2024)As Cath | (Not seen) |
| movie | The Deliverance (2024)As Alberta Jackson | (Not seen) |
| movie | Heart of Stone (2023)As King of Diamonds | (Not seen) |
| tv | The Woman in the House Across the Street from the Girl in the Window (2022)As The Woman in Seat 2A (uncredited)(1 episode) | (Not seen) |
| movie | Swan Song (2021)As Dr. Eve Scott | (Not seen) |
| tv | Tehran (2020) (AKA "טהרן")As Marjan Montazeri(8 episodes) | (Not seen) |
| movie | Disclosure (2020) | (Not seen) |
| movie | Four Good Days (2020)As Deb | (Not seen) |
| movie | Hillbilly Elegy (2020)As Mamaw | (Not seen) |
| movie | Jesus Christ Superstar Live in Concert (2018) | (Not seen) |
| movie | Father Figures (2017)As Helen Baxter | (Not seen) |
| movie | What Happened to Monday (2017)As Nicolette Cayman | (Not seen) |
| movie | The Wife (2017)As Joan Castleman | (Not seen) |
| movie | The Green Fog (2017) | (Not seen) |
| movie | Crooked House (2017)As Lady Edith de Haviland | (Not seen) |
| movie | The Girl with All the Gifts (2016)As Dr. Caroline Caldwell | (Not seen) |
| movie | Warcraft (2016) (AKA "Warcraft: The Beginning")As Alodi | (Not seen) |
| tv | The Late Show with Stephen Colbert (2015)As Self - Guest(1 episode) | (Not seen) |
| tv | Last Week Tonight with John Oliver (2014)As Self(1 episode) | (Not seen) |
| tv | The Tonight Show Starring Jimmy Fallon (2014)As Self(1 episode) | (Not seen) |
| tv | Variety Studio: Actors on Actors (2014)As Self(2 episodes) | (Not seen) |
| tv | Late Night with Seth Meyers (2014)As Self(1 episode) | (Not seen) |
| movie | Guardians of the Galaxy (2014) (AKA "G.O.T.G.")As Nova Prime | (Not seen) |
| movie | Hoodwinked Too! Hood vs. Evil (2011)As Granny (voice) | (Not seen) |
| movie | Albert Nobbs (2011)As Albert Nobbs | (Not seen) |
| tv | The Graham Norton Show (2007)As Self(2 episodes) | (Not seen) |
| movie | Evening (2007)As Mrs. Wittenborn | (Not seen) |
| movie | Tarzan 2: The Legend Begins (2005) (AKA "Tarzan II")As Kala (voice) | (Not seen) |
| movie | The Chumscrubber (2005)As Carrie Johnson | (Not seen) |
| movie | Hoodwinked (2005) (AKA "Hoodwinked!")As Granny (voice) | (Not seen) |
| movie | The Stepford Wives (2004)As Claire Wellington | (Not seen) |
| tv | The Ellen DeGeneres Show (2003)As Self(1 episode) | (Not seen) |
| movie | The Lion in Winter (2003)As Eleanor of Aquitaine | (Not seen) |
| movie | The Divorce (2003) (AKA "Le Divorce")As Olivia Pace | (Not seen) |
| tv | The Shield (2002)As Captain Monica Rawling(13 episodes) | (Not seen) |
| movie | Pinocchio (2002) (AKA "Roberto Benigni's Pinocchio")As Blue Fairy (voice: English version) | (Not seen) |
| movie | The Safety of Objects (2001)As Esther Gold | (Not seen) |
| movie | Things You Can Tell Just by Looking at Her (2000)As Dr. Elaine Keener (segments "This is Dr. Keener" and "Fantasies about Rebecca") | (Not seen) |
| movie | 102 Dalmatians (2000)As Cruella de Vil | (Not seen) |
| tv | Family Guy (1999)As Glenn Close (voice)(1 episode) | (Not seen) |
| tv | The West Wing (1999)As Evelyn Baker Lang(1 episode) | (Not seen) |
| movie | Cookie's Fortune (1999)As Camille Dixon | (Not seen) |
| movie | Tarzan (1999)As Kala (voice) | (Not seen) |
| tv | Will & Grace (1998)As Fannie Lieber(1 episode) | (Not seen) |
| movie | In & Out (1997)As Self | (Not seen) |
| movie | Air Force One (1997) (AKA "AFO")As Vice President Kathryn Bennett | (Not seen) |
| movie | 101 Dalmatians (1996)As Cruella De Vil | (Not seen) |
| movie | Mary Reilly (1996)As Mrs. Farraday | (Not seen) |
| movie | Mars Attacks! (1996)As First Lady Marsha Dale | (Not seen) |
| movie | Serving in Silence: The Margarethe Cammermeyer Story (1995) (AKA "Serving in Silence")As Col. Margarethe Cammermeyer | (Not seen) |
| movie | The House of the Spirits (1993)As Ferula Trueba | (Not seen) |
| movie | Blast 'Em (1992) | (Not seen) |
| movie | Hook (1991)As Gutless | (Not seen) |
| movie | Reversal of Fortune (1990)As Sunny von Bülow / Narrator | (Not seen) |
| movie | Hamlet (1990)As Gertrude | (Not seen) |
| tv | The Simpsons (1989)As Mona Simpson (voice)(13 episodes) | (Not seen) |
| movie | Dangerous Liaisons (1988)As Marquise Isabelle de Merteuil | (Not seen) |
| movie | Fatal Attraction (1987) (AKA "Affairs of the Heart")As Alexandra "Alex" Forrest | (Not seen) |
| movie | Jagged Edge (1985)As Teddy Barnes | (Not seen) |
| movie | The Natural (1984)As Iris Gaines | (Not seen) |
| movie | Greystoke: The Legend of Tarzan, Lord of the Apes (1984)As Miss Jane Porter (voice) (uncredited) | (Not seen) |
| movie | The Big Chill (1983)As Sarah Cooper | (Not seen) |
| movie | The World According to Garp (1982)As Jenny Fields | (Not seen) |
| tv | Saturday Night Live (1975)As Self - Host(2 episodes) | (Not seen) |
| tv | The Oscars (1953)As Self(6 episodes) | (Not seen) |