| Ballad of a Small Player (2025)As Cynthia Blithe | (Not seen) |
| The Room Next Door (2024)As Martha | (Not seen) |
| The Killer (2023)As The Expert | (Not seen) |
| Asteroid City (2023)As Dr. Hickenlooper | (Not seen) |
| Guillermo del Toro's Pinocchio (2022)As (voice) | (Not seen) |
| Three Thousand Years of Longing (2022)As Alithea Binnie | (Not seen) |
| The French Dispatch (2021) (AKA "The French Dispatch of the Liberty, Kansas Evening Sun")As J. K. L. Berensen | (Not seen) |
| Last and First Men (2020)As Narrator (voice) | (Not seen) |
| The Personal History of David Copperfield (2019)As Betsey Trotwood | (Not seen) |
| The Dead Don't Die (2019)As Zelda Winston | (Not seen) |
| Uncut Gems (2019)As Anna (voice) | (Not seen) |
| Avengers: Endgame (2019)As The Ancient One | (Not seen) |
| Suspiria (2018)As Madame Blanc / Dr. Klemperer / Helena Markos | (Not seen) |
| Isle of Dogs (2018)As Oracle (voice) | (Not seen) |
| Okja (2017)As Lucy Mirando / Nancy Mirando | (Not seen) |
| War Machine (2017)As German Politician | (Not seen) |
| Doctor Strange (2016)As The Ancient One | (Not seen) |
| Hail, Caesar! (2016) (AKA "Hail, Caesar! A Tale of The Christ")As Thora Thacker / Thessaly Thacker | (Not seen) |
| A Bigger Splash (2015)As Marianne Lane | (Not seen) |
| Trainwreck (2015)As Dianna | (Not seen) |
| The Grand Budapest Hotel (2014)As Madame Céline Villeneuve Desgoffe-und-Taxis | (Not seen) |
| Only Lovers Left Alive (2013)As Eve | (Not seen) |
| The Zero Theorem (2013)As Dr. Shrink-Rom | (Not seen) |
| Snowpiercer (2013)As Minister Mason | (Not seen) |
| Moonrise Kingdom (2012)As Social Services | (Not seen) |
| We Need to Talk About Kevin (2011)As Eva Khatchadourian | (Not seen) |
| The Chronicles of Narnia: The Voyage of the Dawn Treader (2010)As The White Witch | (Not seen) |
| I Am Love (2009) (AKA "Io sono l'amore")As Emma Recchi | (Not seen) |
| The Limits of Control (2009) (AKA "No Limtis No Control")As Blonde | (Not seen) |
| The Curious Case of Benjamin Button (2008)As Elizabeth Abbott | (Not seen) |
| Burn After Reading (2008)As Katie Cox | (Not seen) |
| The Chronicles of Narnia: Prince Caspian (2008) (AKA "Prince Caspian")As White Witch | (Not seen) |
| Michael Clayton (2007)As Karen Crowder | (Not seen) |
| Broken Flowers (2005)As Penny | (Not seen) |
| Thumbsucker (2005)As Audrey Cobb | (Not seen) |
| The Chronicles of Narnia: The Lion, the Witch and the Wardrobe (2005) (AKA "The Chronicles of Narnia")As White Witch | (Not seen) |
| Constantine (2005)As Gabriel | (Not seen) |
| Young Adam (2003)As Ella Gault | (Not seen) |
| Adaptation. (2002) (AKA "The Orchid Thief")As Valerie Thomas | (Not seen) |
| The Deep End (2001)As Margaret Hall | (Not seen) |
| Vanilla Sky (2001)As Rebecca Dearborn | (Not seen) |
| Possible Worlds (2000)As Joyce | (Not seen) |
| The Beach (2000)As Sal | (Not seen) |
| The Protagonists (1999)As Actress | (Not seen) |
| Wittgenstein (1993)As Lady Ottoline Morrell | (Not seen) |
| Orlando (1992)As Orlando | (Not seen) |
| The Garden (1990)As Madonna/Voice Overs | (Not seen) |
| War Requiem (1989)As The Nurse | (Not seen) |
| The Last of England (1987)As The Maid | (Not seen) |
| Caravaggio (1986)As Lena | (Not seen) |