| tv | Everybody's Live with John Mulaney (2025)As Self - Director, Performer and Writer(1 episode) | (Not seen) |
| movie | The Bad Guys 2 (2025)As Doom (voice) | (Not seen) |
| movie | Smurfs (2025)As Mama Poot (voice) | (Not seen) |
| movie | SNL50: The Homecoming Concert (2025) | (Not seen) |
| movie | The Fantastic Four: First Steps (2025) (AKA "The Fantastic 4: First Steps")As Rachel Rozman | (Not seen) |
| tv | Fantasmas (2024)As Suzanna(6 episodes) | (Not seen) |
| movie | An Almost Christmas Story (2024)As Pat (voice) | (Not seen) |
| tv | Poker Face (2023)As Charlie Cale(22 episodes) | (Not seen) |
| movie | His Three Daughters (2023)As Rachel | (Not seen) |
| movie | Glass Onion (2022) (AKA "Glass Onion: A Knives Out Mystery")As Natasha Lyonne | (Not seen) |
| movie | DC League of Super-Pets (2022)As Merton (voice) | (Not seen) |
| tv | What If...? (2021)As Byrdie (voice)(2 episodes) | (Not seen) |
| movie | Have a Good Trip (2020) (AKA "Have a Good Trip: Adventures in Psychedelics")As Self | (Not seen) |
| movie | Irresistible (2020)As Tina | (Not seen) |
| tv | Russian Doll (2019)As Nadia Vulvokov(15 episodes) | (Not seen) |
| movie | Honey Boy (2019)As Mom | (Not seen) |
| movie | Uncut Gems (2019)As Boston Player Personnel (voice) | (Not seen) |
| movie | Ad Astra (2019)As Tanya Pincus | (Not seen) |
| tv | Explained (2018)As Narrator (voice)(1 episode) | (Not seen) |
| movie | A Futile and Stupid Gesture (2018)As Anne Beatts | (Not seen) |
| tv | Big Mouth (2017)As Suzette (voice)(6 episodes) | (Not seen) |
| movie | Handsome: A Netflix Mystery Movie (2017)As Detective Fleur Scozzari | (Not seen) |
| movie | Yoga Hosers (2016)As Tabitha | (Not seen) |
| movie | Jack Goes Home (2016)As Nancy | (Not seen) |
| tv | Documentary Now! (2015)As Carla Meola(1 episode) | (Not seen) |
| tv | Taskmaster (2015)As Self | (Not seen) |
| tv | The Late Late Show with James Corden (2015)As Self - Guest(1 episode) | (Not seen) |
| tv | The Late Show with Stephen Colbert (2015)As Self(1 episode) | (Not seen) |
| movie | #Horror (2015)As Emma | (Not seen) |
| movie | Addicted to Fresno (2015)As Martha | (Not seen) |
| movie | Sleeping with Other People (2015)As Kara | (Not seen) |
| tv | The Tonight Show Starring Jimmy Fallon (2014)As Self - Guest(4 episodes) | (Not seen) |
| tv | Variety Studio: Actors on Actors (2014)As Self(2 episodes) | (Not seen) |
| tv | Late Night with Seth Meyers (2014)As Self(3 episodes) | (Not seen) |
| tv | Steven Universe (2013)As Smoky Quartz (voice)(3 episodes) | (Not seen) |
| tv | Orange Is the New Black (2013)As Nicky Nichols(81 episodes) | (Not seen) |
| movie | G.B.F. (2013)As Mrs. Hoegel | (Not seen) |
| tv | The Eric Andre Show (2012)As Self(1 episode) | (Not seen) |
| tv | Girls (2012)As Rickey(1 episode) | (Not seen) |
| movie | Girl Most Likely (2012)As Allyson | (Not seen) |
| movie | American Reunion (2012) (AKA "American Pie: Reunion")As Jessica | (Not seen) |
| tv | Portlandia (2011)As Madison(4 episodes) | (Not seen) |
| tv | New Girl (2011)As Gretchen(1 episode) | (Not seen) |
| tv | RuPaul's Drag Race (2009)As Self - Guest Judge(1 episode) | (Not seen) |
| tv | Weeds (2005)As Tiffany(1 episode) | (Not seen) |
| movie | Robots (2005)As Loretta Geargrinder (voice) | (Not seen) |
| movie | Madhouse (2004) (AKA "Mad Cannibal")As Alice | (Not seen) |
| movie | Blade: Trinity (2004) (AKA "Blade III")As Sommerfield | (Not seen) |
| movie | Party Monster (2003)As Brooke | (Not seen) |
| movie | Comic Book Villains (2002)As Judy | (Not seen) |
| movie | Zig Zag (2002)As Jenna the Working Girl | (Not seen) |
| movie | The Grey Zone (2001)As Rosa | (Not seen) |
| movie | American Pie 2 (2001) (AKA "Secret Disguise")As Jessica | (Not seen) |
| movie | Kate & Leopold (2001) (AKA "Kate and Leopold")As Darci | (Not seen) |
| movie | Scary Movie 2 (2001)As Megan | (Not seen) |
| tv | Law & Order: Special Victims Unit (1999)As Gia Eskas(1 episode) | (Not seen) |
| movie | Detroit Rock City (1999)As Christine | (Not seen) |
| movie | Freeway II: Confessions of a Trickbaby (1999) (AKA "Freeway 2: Confessions of a Trickbaby")As White Girl | (Not seen) |
| movie | American Pie (1999) (AKA "East Great Falls High")As Jessica | (Not seen) |
| tv | Will & Grace (1998)As Gillian(1 episode) | (Not seen) |
| movie | Slums of Beverly Hills (1998)As Vivian Abromowitz | (Not seen) |
| movie | Modern Vampires (1998) (AKA "Revenant")As Rachel | (Not seen) |
| movie | Everyone Says I Love You (1996)As Djuna 'D.J.' Berlin | (Not seen) |
| movie | Dennis the Menace (1993) (AKA "Dennis")As Polly | (Not seen) |
| tv | The Simpsons (1989)As Sophie (voice)(4 episodes) | (Not seen) |
| tv | Saturday Night Live (1975)As Self - Host(2 episodes) | (Not seen) |