| tv | Based on a True Story (2023)As Narrator (voice) | (Not seen) |
| tv | Big Shot (2021)As Dr. Harriman | (Not seen) |
| movie | The God Committee (2021)As Dr. Valerie Gilroy | (Not seen) |
| tv | Stumptown (2019)As Janet Withers(1 episode) | (Not seen) |
| tv | Harley Quinn (2019)As Signora/Mama (voice)(1 episode) | (Not seen) |
| movie | Come As You Are (2019)As Liz | (Not seen) |
| tv | Wet Hot American Summer: Ten Years Later (2017)As Beth(8 episodes) | (Not seen) |
| movie | Michael Bolton's Big, Sexy Valentine's Day Special (2017)As Janeane Garofalo | (Not seen) |
| movie | Sandy Wexler (2017)As Testimonial | (Not seen) |
| tv | Billions (2016)As Winslow(2 episodes) | (Not seen) |
| movie | The American Side (2016)As Agent Barry | (Not seen) |
| tv | Wet Hot American Summer: First Day of Camp (2015)As Beth(8 episodes) | (Not seen) |
| tv | Broad City (2014)As Monica(3 episodes) | (Not seen) |
| tv | BoJack Horseman (2014)As Isabelle (voice)(1 episode) | (Not seen) |
| tv | @midnight with Chris Hardwick (2013)As Self(1 episode) | (Not seen) |
| movie | Free the Nipple (2013)As Anouk | (Not seen) |
| movie | Bad Parents (2012)As Kathy | (Not seen) |
| tv | The Increasingly Poor Decisions of Todd Margaret (2010)As Brent's Boss(1 episode) | (Not seen) |
| movie | Love Hurts (2009)As Hannah Rosenbloom | (Not seen) |
| movie | Funny People (2009)As Friend in video (archive footage) (uncredited) | (Not seen) |
| movie | Tropic Thunder: Rain of Madness (2008)As Heidi Bivens | (Not seen) |
| movie | Then She Found Me (2007)As Self | (Not seen) |
| movie | The Ten (2007)As Nuclear Powerplant Shift Supervisor Beth Soden | (Not seen) |
| movie | Ratatouille (2007)As Colette (voice) | (Not seen) |
| movie | Southland Tales (2006)As General Teena MacArthur | (Not seen) |
| movie | The Wild (2006) (AKA "La vie sauvage")As Bridget (voice) | (Not seen) |
| movie | Duane Hopwood (2005)As Linda | (Not seen) |
| movie | Stay (2005)As Dr. Beth Levy | (Not seen) |
| tv | Real Time with Bill Maher (2003)As Self(6 episodes) | (Not seen) |
| tv | Two and a Half Men (2003)As Sharon(1 episode) | (Not seen) |
| movie | Wonderland (2003) (AKA "The Wonderland Murders")As Joy Miller | (Not seen) |
| movie | The Laramie Project (2002)As Catherine Connolly | (Not seen) |
| movie | Big Trouble (2002)As Officer Monica Romero | (Not seen) |
| tv | 24 (2001)As Janis Gold(24 episodes) | (Not seen) |
| movie | Wet Hot American Summer (2001)As Beth | (Not seen) |
| movie | What Planet Are You From? (2000)As Nervous Woman | (Not seen) |
| movie | The Adventures of Rocky & Bullwinkle (2000)As Minnie Mogul | (Not seen) |
| movie | Titan A.E. (2000) (AKA "Planet Ice")As Stith (voice) | (Not seen) |
| tv | The Sopranos (1999)As Self(1 episode) | (Not seen) |
| tv | The West Wing (1999)As Louise Thornton(15 episodes) | (Not seen) |
| movie | The Minus Man (1999)As Ferrin | (Not seen) |
| movie | Dogma (1999) (AKA "Bearclaw")As Liz | (Not seen) |
| movie | Mystery Men (1999)As The Bowler | (Not seen) |
| movie | 200 Cigarettes (1999) (AKA "The Islander")As Ellie | (Not seen) |
| movie | Clay Pigeons (1998) (AKA "Moonlight Drive")As Agent Dale Shelby | (Not seen) |
| movie | Permanent Midnight (1998)As Jana Farmer | (Not seen) |
| movie | Half Baked (1998)As I'm Only Creative When I Smoke Smoker | (Not seen) |
| tv | King of the Hill (1997)As Sheila (voice)(1 episode) | (Not seen) |
| movie | Sweethearts (1997)As Jasmine | (Not seen) |
| movie | The MatchMaker (1997)As Marcy Tizard | (Not seen) |
| movie | Cop Land (1997) (AKA "CopLand")As Deputy Cindy Betts | (Not seen) |
| movie | Romy and Michele's High School Reunion (1997)As Heather Mooney | (Not seen) |
| tv | The Daily Show (1996)As Self(1 episode) | (Not seen) |
| movie | Larger Than Life (1996) (AKA "Large as Life")As Mo | (Not seen) |
| movie | The Truth About Cats & Dogs (1996)As Dr. Abby Barnes | (Not seen) |
| movie | The Cable Guy (1996)As Medieval Times Waitress | (Not seen) |
| movie | Coldblooded (1995)As Honey | (Not seen) |
| movie | Now and Then (1995) (AKA "Dear Friends")As Wiladene | (Not seen) |
| movie | Bye Bye Love (1995)As Lucille | (Not seen) |
| movie | Reality Bites (1994)As Vickie Miner | (Not seen) |
| tv | The Larry Sanders Show (1992)As Paula(65 episodes) | (Not seen) |
| tv | Home Improvement (1991)As Tina(1 episode) | (Not seen) |
| tv | Law & Order (1990)As Greta Heiss(2 episodes) | (Not seen) |
| tv | The Simpsons (1989)As Janeane Garofalo (voice)(2 episodes) | (Not seen) |
| tv | Seinfeld (1989)As Jeannie Steinman(2 episodes) | (Not seen) |
| movie | Kiki's Delivery Service (1989) | (Not seen) |
| tv | Saturday Night Live (1975)As Self - Various Characters(14 episodes) | (Not seen) |