| movie | Shrek 5 (2026)As Puss in Boots (voice) | (Not seen) |
| movie | The Clean Up Crew (2024)As Gabriel | (Not seen) |
| movie | Cult Killer (2024)As Mikeal Tallini | (Not seen) |
| movie | Babygirl (2024)As Jacob | (Not seen) |
| movie | Paddington in Peru (2024)As Hunter Cabot | (Not seen) |
| movie | Indiana Jones and the Dial of Destiny (2023) (AKA "Untitled Indiana Jones Project")As Renaldo | (Not seen) |
| movie | Code Name Banshee (2022)As Caleb | (Not seen) |
| movie | Puss in Boots: The Last Wish (2022)As Puss in Boots (voice) | (Not seen) |
| movie | Uncharted (2022)As Santiago Moncada | (Not seen) |
| movie | Hitman's Wife's Bodyguard (2021)As Aristotle Papdopolous | (Not seen) |
| movie | Dolittle (2020)As King Rassouli | (Not seen) |
| movie | Pain and Glory (2019)As Salvador Mallo | (Not seen) |
| movie | The Laundromat (2019)As Ramón Fonseca | (Not seen) |
| movie | Gun Shy (2017)As Turk Henry | (Not seen) |
| movie | Black Butterfly (2017)As Paul | (Not seen) |
| movie | Security (2017)As Eduardo 'Eddie' Deacon | (Not seen) |
| movie | Acts of Vengeance (2017)As Frank Valera | (Not seen) |
| movie | Bullet Head (2017)As Blue | (Not seen) |
| tv | The Late Show with Stephen Colbert (2015)As Self(3 episodes) | (Not seen) |
| movie | The SpongeBob Movie: Sponge Out of Water (2015) (AKA "The SpongeBob SquarePants Movie 2")As Burger Beard | (Not seen) |
| movie | The 33 (2015)As Mario Sepúlveda | (Not seen) |
| tv | Variety Studio: Actors on Actors (2014)As Self(1 episode) | (Not seen) |
| movie | Automata (2014)As Jacq Vaucan | (Not seen) |
| movie | The Expendables 3 (2014)As Galgo | (Not seen) |
| movie | Machete Kills (2013)As El Camaleon | (Not seen) |
| movie | Ruby Sparks (2012)As Mort | (Not seen) |
| movie | Spy Kids 4: All the Time in the World (2011) (AKA "Spy Kids: All the Time in the World")As Gregorio Cortez (uncredited) | (Not seen) |
| movie | Day of the Falcon (2011) (AKA "Black Gold")As Emir Nesib | (Not seen) |
| movie | Puss in Boots (2011)As Puss in Boots (voice) | (Not seen) |
| movie | Haywire (2011)As Rodrigo | (Not seen) |
| movie | The Skin I Live In (2011) (AKA "La piel que habito")As Dr Robert Ledgard | (Not seen) |
| movie | The Big Bang (2010)As Ned Cruz | (Not seen) |
| movie | You Will Meet a Tall Dark Stranger (2010)As Greg | (Not seen) |
| movie | Shrek Forever After (2010) (AKA "Forever After: The Final Chapter")As Puss in Boots (voice) | (Not seen) |
| movie | Aliens in the Attic (2009) | (Not seen) |
| movie | The Code (2009) (AKA "Thick as Thieves")As Gabriel Martin | (Not seen) |
| movie | My Mom's New Boyfriend (2008)As Thomas Martins | (Not seen) |
| movie | The Other Man (2008)As Ralph | (Not seen) |
| tv | The Graham Norton Show (2007)As Self(1 episode) | (Not seen) |
| movie | Shrek the Halls (2007)As Puss in Boots (voice) | (Not seen) |
| movie | Shrek the Third (2007) (AKA "Shrek 3")As Puss in Boots (voice) | (Not seen) |
| movie | Take the Lead (2006)As Pierre Dulaine | (Not seen) |
| movie | The Legend of Zorro (2005) (AKA "Zorro Unmasked")As Don Alejandro de la Vega / Zorro | (Not seen) |
| movie | Shrek 2 (2004)As Puss in Boots (voice) | (Not seen) |
| tv | The Ellen DeGeneres Show (2003)As Self(2 episodes) | (Not seen) |
| movie | Spy Kids 3: Game Over (2003) (AKA "Spy Kids 3-D: Game Over")As Gregorio Cortez | (Not seen) |
| movie | Once Upon a Time in Mexico (2003) (AKA "El Mariachi 3")As El Mariachi | (Not seen) |
| tv | American Idol (2002)As Self(1 episode) | (Not seen) |
| movie | Spy Kids 2: Island of Lost Dreams (2002) (AKA "Spy Kids 2: The Island of Lost Dreams")As Gregorio Cortez | (Not seen) |
| movie | Femme Fatale (2002)As Nicolas Bardo | (Not seen) |
| movie | Frida (2002)As David Alfaro Siqueiros | (Not seen) |
| movie | Ballistic: Ecks vs. Sever (2002) (AKA "Ballistic")As Agent Jeremiah Ecks | (Not seen) |
| movie | The Body (2001)As Father Matt Gutierrez | (Not seen) |
| movie | Spy Kids (2001)As Gregorio Cortez | (Not seen) |
| movie | The White River Kid (1999) (AKA "White River")As Morales Pittman | (Not seen) |
| movie | Play It to the Bone (1999) (AKA "Play It")As Cesar Dominguez | (Not seen) |
| movie | The 13th Warrior (1999) (AKA "Eaters of the Dead")As Ahmad Ibn Fadlān | (Not seen) |
| movie | The Mask of Zorro (1998) (AKA "Die Maske des Zorro")As Alejandro Murrieta / Zorro | (Not seen) |
| movie | Evita (1996)As Ché | (Not seen) |
| movie | Never Talk to Strangers (1995)As Tony Ramirez | (Not seen) |
| movie | Miami Rhapsody (1995)As Antonio | (Not seen) |
| movie | The Celluloid Closet (1995) | (Not seen) |
| movie | Four Rooms (1995) (AKA "Four Rooms and a Hotel")As Man | (Not seen) |
| movie | Assassins (1995)As Miguel Bain | (Not seen) |
| movie | Desperado (1995) (AKA "El Mariachi 2")As El Mariachi | (Not seen) |
| movie | Interview with the Vampire (1994)As Armand | (Not seen) |
| movie | The House of the Spirits (1993)As Pedro Tercero Gareia | (Not seen) |
| movie | Philadelphia (1993) (AKA "At Risk")As Miguel Alvarez | (Not seen) |
| movie | Madonna: Truth or Dare (1991)As Self | (Not seen) |
| movie | Tie Me Up! Tie Me Down! (1989) (AKA "Atame!")As Ricky | (Not seen) |
| movie | Women on the Verge of a Nervous Breakdown (1988) (AKA "Mujeres al borde de un ataque de nervios")As Carlos | (Not seen) |
| movie | Law of Desire (1987) (AKA "La ley del deseo")As Antonio Benítez | (Not seen) |
| movie | Matador (1986)As Angel | (Not seen) |
| movie | Labyrinth of Passion (1982)As Sadec | (Not seen) |
| tv | Saturday Night Live (1975)As Self - Host(1 episode) | (Not seen) |
| tv | The Oscars (1953)As Self(6 episodes) | (Not seen) |