| movie | The Roses (2025)As Eleanor | (Not seen) |
| movie | Another Simple Favor (2025)As Aunt Linda McLanden | (Not seen) |
| tv | The Diplomat (2023)As Vice President Grace Penn(6 episodes) | (Not seen) |
| movie | The Creator (2023)As Colonel Howell | (Not seen) |
| movie | To Leslie (2022)As Nancy | (Not seen) |
| movie | The People We Hate at the Wedding (2022)As Donna | (Not seen) |
| movie | Lou (2022)As Lou | (Not seen) |
| movie | Breaking News in Yuba County (2021)As Sue Buttons | (Not seen) |
| movie | A West Wing Special to Benefit When We All Vote (2020)As C.J. Cregg | (Not seen) |
| movie | Ma (2019)As Doctor Brooks | (Not seen) |
| movie | Bad Education (2019)As Pam Gluckin | (Not seen) |
| movie | Bombshell (2019)As Susan Estrich | (Not seen) |
| movie | The Addams Family (2019)As Margaux Needler (voice) | (Not seen) |
| tv | The Kominsky Method (2018)As Self(1 episode) | (Not seen) |
| movie | I, Tonya (2017)As LaVona Golden | (Not seen) |
| tv | Chelsea (2016)As Self(1 episode) | (Not seen) |
| movie | Miss Peregrine's Home for Peculiar Children (2016)As Dr. Golan | (Not seen) |
| movie | The Girl on the Train (2016)As Detective Sgt. Riley | (Not seen) |
| movie | Finding Dory (2016)As Peach (voice) | (Not seen) |
| tv | The Late Late Show with James Corden (2015)As Self(4 episodes) | (Not seen) |
| tv | The Late Show with Stephen Colbert (2015)As Self(1 episode) | (Not seen) |
| movie | The DUFF (2015)As Dottie Piper | (Not seen) |
| movie | Minions (2015)As Madge Nelson (voice) | (Not seen) |
| movie | Spy (2015)As Elaine Crocker | (Not seen) |
| tv | Variety Studio: Actors on Actors (2014)As Self(1 episode) | (Not seen) |
| tv | Late Night with Seth Meyers (2014)As Self(1 episode) | (Not seen) |
| movie | The Rewrite (2014)As Mary Weldon | (Not seen) |
| movie | Mr. Peabody & Sherman (2014)As Ms. Grunion (voice) | (Not seen) |
| movie | Tammy (2014)As Deb | (Not seen) |
| tv | Masters of Sex (2013)As Margaret Scully(9 episodes) | (Not seen) |
| movie | Bad Words (2013)As Dr. Bernice Deagan | (Not seen) |
| movie | Trust Me (2013)As Meg | (Not seen) |
| movie | The Way Way Back (2013) (AKA "The Way, Way Back")As Betty Thompson | (Not seen) |
| tv | Veep (2012)As Janet Ryland(1 episode) | (Not seen) |
| movie | A Thousand Words (2012)As Samantha Davis | (Not seen) |
| movie | Liberal Arts (2012)As Professor Judith Fairfield | (Not seen) |
| tv | Mr. Sunshine (2011)As Crystal Cohen(9 episodes) | (Not seen) |
| movie | The Help (2011)As Charlotte Phelan | (Not seen) |
| movie | Life During Wartime (2009)As Trish | (Not seen) |
| movie | Away We Go (2009)As Lily | (Not seen) |
| movie | Pretty Ugly People (2008)As Suzanna | (Not seen) |
| tv | The Graham Norton Show (2007)As Self(1 episode) | (Not seen) |
| tv | Phineas and Ferb (2007)As Charlene Doofenshmirtz (voice)(2 episodes) | (Not seen) |
| movie | Juno (2007)As Bren MacGuff | (Not seen) |
| movie | Hairspray (2007)As Prudy Pringleton | (Not seen) |
| tv | Studio 60 on the Sunset Strip (2006)As Self(1 episode) | (Not seen) |
| movie | Over the Hedge (2006)As Gladys (voice) | (Not seen) |
| tv | Weeds (2005)As Ms. Greenstein(1 episode) | (Not seen) |
| movie | Strangers with Candy (2005)As Alice | (Not seen) |
| movie | The Chumscrubber (2005)As Allie Stiffle | (Not seen) |
| tv | Lost (2004)As Mother(1 episode) | (Not seen) |
| tv | Two and a Half Men (2003)As Beverly(1 episode) | (Not seen) |
| tv | The Ellen DeGeneres Show (2003)As Self(7 episodes) | (Not seen) |
| movie | Finding Nemo (2003)As Peach (voice) | (Not seen) |
| movie | The Hours (2002)As Sally Lester | (Not seen) |
| tv | Curb Your Enthusiasm (2000)As Cynthia(1 episode) | (Not seen) |
| movie | Nurse Betty (2000)As Lyla Branch | (Not seen) |
| tv | Family Guy (1999)As Teen People Editor (voice)(3 episodes) | (Not seen) |
| tv | The West Wing (1999)As C.J. Cregg(154 episodes) | (Not seen) |
| movie | Drop Dead Gorgeous (1999)As Loretta | (Not seen) |
| movie | American Beauty (1999)As Barbara Fitts | (Not seen) |
| movie | 10 Things I Hate About You (1999)As Ms. Perky | (Not seen) |
| movie | Celebrity (1998)As Evelyn Isaacs | (Not seen) |
| movie | The Object of My Affection (1998)As Constance Miller | (Not seen) |
| movie | Six Days Seven Nights (1998) (AKA "6 Days 7 Nights")As Marjorie | (Not seen) |
| movie | Primary Colors (1998)As Miss Walsh | (Not seen) |
| tv | King of the Hill (1997)As Laura (voice)(1 episode) | (Not seen) |
| movie | The Ice Storm (1997)As Dot Halford | (Not seen) |
| movie | Private Parts (1997) (AKA "Howard Stern's Private Parts")As Dee Dee | (Not seen) |
| tv | The Daily Show (1996)As Self(1 episode) | (Not seen) |
| movie | Miracle on 34th Street (1994)As Woman in Christmas Shop | (Not seen) |
| movie | The Cowboy Way (1994)As NYPD Computer Operator | (Not seen) |
| movie | Wolf (1994)As Party Guest | (Not seen) |
| tv | Frasier (1993)As Susanna(2 episodes) | (Not seen) |
| tv | Law & Order (1990)As Nora(2 episodes) | (Not seen) |
| tv | The Simpsons (1989)As Julia (voice)(1 episode) | (Not seen) |
| tv | Saturday Night Live (1975)As Self - Cameo (uncredited)(1 episode) | (Not seen) |
| tv | The Oscars (1953)As Self(1 episode) | (Not seen) |