| tv | Hot Ones Versus (2024)As Self(1 episode) | (Not seen) |
| tv | Agatha All Along (2024)As Lilia Calderu(9 episodes) | (Not seen) |
| movie | Beau Is Afraid (2023)As Beau's Mom | (Not seen) |
| tv | Curtain Call (2022) (AKA "커튼콜: 나무는 서서 죽는다")As Emmy Cosell | (Not seen) |
| movie | The School for Good and Evil (2022)As Mrs. Deauville | (Not seen) |
| tv | Penny Dreadful: City of Angels (2020)As Vocalist(1 episode) | (Not seen) |
| tv | Hollywood (2020)As Avis Amberg(7 episodes) | (Not seen) |
| movie | Last Christmas (2019)As Joyce | (Not seen) |
| tv | POSE (2018)As Frederica Norman(4 episodes) | (Not seen) |
| movie | The Comedian (2016)As Florence Berkowitz | (Not seen) |
| tv | The Late Show with Stephen Colbert (2015)As Self(1 episode) | (Not seen) |
| tv | Penny Dreadful (2014)As Dr. Seward(10 episodes) | (Not seen) |
| tv | BoJack Horseman (2014)As Mimi Stilton (voice)(1 episode) | (Not seen) |
| tv | Late Night with Seth Meyers (2014)As Self(1 episode) | (Not seen) |
| tv | Steven Universe (2013)As Yellow Diamond (voice)(8 episodes) | (Not seen) |
| movie | Parker (2013)As Ascension | (Not seen) |
| tv | American Horror Story (2011)As Kathy Pizazz(13 episodes) | (Not seen) |
| tv | Glee (2009)As Patti LuPone(1 episode) | (Not seen) |
| tv | 30 Rock (2006)As Sylvia Rossitano(3 episodes) | (Not seen) |
| movie | City by the Sea (2002) (AKA "Mark of a Murderer")As Maggie | (Not seen) |
| movie | Heist (2001) (AKA "Le vol")As Betty Croft | (Not seen) |
| movie | State and Main (2000)As Sherry Bailey | (Not seen) |
| tv | Law & Order: Special Victims Unit (1999)As Lydia Lebasi(1 episode) | (Not seen) |
| movie | Summer of Sam (1999) (AKA "The Son of Sam")As Helen | (Not seen) |
| tv | Will & Grace (1998)As Patti LuPone(1 episode) | (Not seen) |
| tv | Frasier (1993)As Zora Crane(2 episodes) | (Not seen) |
| tv | Law & Order (1990)As Ruth Miller(2 episodes) | (Not seen) |
| tv | The Simpsons (1989)As Cheryl Monroe (voice)(1 episode) | (Not seen) |
| movie | Driving Miss Daisy (1989)As Florine Werthan | (Not seen) |
| movie | Wise Guys (1986)As Wanda Valentini | (Not seen) |
| movie | Witness (1985) (AKA "Called Home")As Elaine | (Not seen) |
| movie | 1941 (1979) (AKA "The Night the Japs Attacked")As Lydia Hedberg | (Not seen) |
| tv | Saturday Night Live (1975)As Self - Cameo (uncredited)(1 episode) | (Not seen) |