| movie | Wolfs (2024)As Pam (voice) | (Not seen) |
| movie | Women Talking (2022)As Scarface Janz | (Not seen) |
| movie | The Tragedy of Macbeth (2021)As Lady Macbeth | (Not seen) |
| movie | The French Dispatch (2021) (AKA "The French Dispatch of the Liberty, Kansas Evening Sun")As Lucinda Krementz | (Not seen) |
| movie | Nomadland (2020)As Fern | (Not seen) |
| tv | Good Omens (2019)As God (voice)(7 episodes) | (Not seen) |
| movie | Isle of Dogs (2018)As Interpreter Nelson (voice) | (Not seen) |
| movie | Three Billboards Outside Ebbing, Missouri (2017)As Mildred Hayes | (Not seen) |
| movie | Hail, Caesar! (2016) (AKA "Hail, Caesar! A Tale of The Christ")As C. C. Calhoun | (Not seen) |
| movie | The Good Dinosaur (2015)As Momma (voice) | (Not seen) |
| movie | Every Secret Thing (2014) | (Not seen) |
| movie | Madagascar 3: Europe's Most Wanted (2012)As Captain Chantel DuBois (voice) | (Not seen) |
| movie | Promised Land (2012)As Sue Thomason | (Not seen) |
| movie | Moonrise Kingdom (2012)As Mrs. Bishop | (Not seen) |
| movie | This Must Be the Place (2011)As Jane | (Not seen) |
| movie | Transformers: Dark of the Moon (2011)As Mearing | (Not seen) |
| movie | Miss Pettigrew Lives for a Day (2008)As Guinevere Pettigrew | (Not seen) |
| movie | Burn After Reading (2008)As Linda Litzke | (Not seen) |
| movie | Friends with Money (2006)As Jane | (Not seen) |
| movie | North Country (2005)As Glory | (Not seen) |
| movie | Æon Flux (2005)As Handler | (Not seen) |
| movie | Something's Gotta Give (2003)As Zoe | (Not seen) |
| movie | Laurel Canyon (2002)As Jane | (Not seen) |
| movie | City by the Sea (2002) (AKA "Mark of a Murderer")As Michelle | (Not seen) |
| movie | The Man Who Wasn't There (2001)As Doris Crane | (Not seen) |
| movie | Wonder Boys (2000)As Dean Sara Gaskell | (Not seen) |
| movie | Almost Famous (2000) (AKA "Something Real")As Elaine Miller | (Not seen) |
| movie | Johnny Skidmarks (1998)As Alice | (Not seen) |
| movie | Lone Star (1996)As Bunny | (Not seen) |
| movie | Fargo (1996)As Marge Gunderson | (Not seen) |
| movie | Primal Fear (1996)As Molly Arrington | (Not seen) |
| movie | Short Cuts (1993)As Betty Weathers | (Not seen) |
| movie | Barton Fink (1991)As Stage Actress (voice) | (Not seen) |
| movie | Hidden Agenda (1990)As Ingrid Jessner | (Not seen) |
| movie | Miller's Crossing (1990)As Mayor's secretary (uncredited) | (Not seen) |
| movie | Darkman (1990)As Julie Hastings | (Not seen) |
| tv | The Simpsons (1989)As Melanie Upfoot (voice)(1 episode) | (Not seen) |
| movie | Mississippi Burning (1988)As Mrs. Pell | (Not seen) |
| movie | Raising Arizona (1987)As Dot | (Not seen) |
| movie | Crimewave (1985)As Nun | (Not seen) |
| movie | Blood Simple (1984)As Abby | (Not seen) |
| tv | The Oscars (1953)As Self(6 episodes) | (Not seen) |