| movie | Hoppers (2026)As Insect Queen (voice) | (Not seen) |
| movie | The Devil Wears Prada 2 (2026)As Miranda Priestly | (Not seen) |
| movie | Project Hail Mary (2026)As Rejected Rocky voice (voice) | (Not seen) |
| movie | SNL50: The Homecoming Concert (2025)As Self | (Not seen) |
| tv | Extrapolations (2023)As Eve(1 episode) | (Not seen) |
| movie | Albert Brooks: Defending My Life (2023) | (Not seen) |
| tv | Only Murders in the Building (2021)As Loretta Durkin(11 episodes) | (Not seen) |
| movie | Don't Look Up (2021)As President Orlean | (Not seen) |
| tv | Unsolved Mysteries (2020)As Herself | (Not seen) |
| movie | Little Women (2019)As Aunt Josephine March | (Not seen) |
| movie | The Laundromat (2019)As Ellen Martin / Elena | (Not seen) |
| movie | Mary Poppins Returns (2018)As Tatiana "Topsy" Topotrepolovsky | (Not seen) |
| movie | Mamma Mia! Here We Go Again (2018)As Donna | (Not seen) |
| tv | Big Little Lies (2017)As Mary Louise Wright(7 episodes) | (Not seen) |
| movie | The Post (2017)As Kay Graham | (Not seen) |
| movie | Bright Lights: Starring Carrie Fisher and Debbie Reynolds (2016) | (Not seen) |
| tv | The Late Late Show with James Corden (2015)As Self(1 episode) | (Not seen) |
| movie | Suffragette (2015)As Emmeline Pankhurst | (Not seen) |
| movie | Ricki and the Flash (2015)As Ricki Rendazzo | (Not seen) |
| movie | The Homesman (2014)As Altha Carter | (Not seen) |
| movie | Into the Woods (2014)As Witch | (Not seen) |
| movie | The Giver (2014)As Chief Elder | (Not seen) |
| movie | August: Osage County (2013)As Violet Weston | (Not seen) |
| movie | Hope Springs (2012)As Kay | (Not seen) |
| movie | The Iron Lady (2011)As Margaret Thatcher | (Not seen) |
| movie | Higglety Pigglety Pop! or There Must Be More to Life (2010)As Jennie | (Not seen) |
| movie | Julie & Julia (2009)As Julia Child | (Not seen) |
| movie | It's Complicated (2009)As Jane Adler | (Not seen) |
| movie | Fantastic Mr. Fox (2009)As Felicity Fox (voice) | (Not seen) |
| movie | Doubt (2008)As Sister Aloysius Beauvier | (Not seen) |
| movie | Mamma Mia! (2008) (AKA "Mamma Mia! The Movie")As Donna Sheridan | (Not seen) |
| tv | The Graham Norton Show (2007)As Self(3 episodes) | (Not seen) |
| movie | Evening (2007)As Lila Ross | (Not seen) |
| movie | Lions for Lambs (2007)As Janine Roth | (Not seen) |
| movie | Rendition (2007)As Corrine Whitman | (Not seen) |
| movie | The Ant Bully (2006)As Queen (voice) | (Not seen) |
| movie | A Prairie Home Companion (2006)As Yolanda Johnson | (Not seen) |
| movie | The Devil Wears Prada (2006)As Miranda Priestly | (Not seen) |
| movie | Prime (2005)As Lisa Metzger | (Not seen) |
| movie | A Series of Unfortunate Events (2004) (AKA "Lemony Snicket's A Series of Unfortunate Events")As Josephine Anwhistle | (Not seen) |
| movie | The Manchurian Candidate (2004)As Senator Eleanor Prentiss Shaw (D-VA) | (Not seen) |
| tv | Angels in America (2003)As Hannah Pitt / Ethel Rosenberg / The Rabbi / The Angel Australia(6 episodes) | (Not seen) |
| tv | The Ellen DeGeneres Show (2003)As Self(2 episodes) | (Not seen) |
| movie | Stuck on You (2003)As Meryl Streep (uncredited) | (Not seen) |
| movie | The Hours (2002)As Clarissa Vaughan | (Not seen) |
| movie | Adaptation. (2002) (AKA "The Orchid Thief")As Susan Orlean | (Not seen) |
| movie | A.I. Artificial Intelligence (2001) (AKA "A.I.")As Blue Mecha (voice) | (Not seen) |
| movie | Music of the Heart (1999)As Roberta Guaspari | (Not seen) |
| movie | Dancing at Lughnasa (1998)As Kate Mundy | (Not seen) |
| tv | King of the Hill (1997)As Aunt Esme Dauterive (voice)(1 episode) | (Not seen) |
| tv | The Daily Show (1996)As Self(1 episode) | (Not seen) |
| movie | Before and After (1996)As Dr. Carolyn Ryan | (Not seen) |
| movie | Marvin's Room (1996) (AKA "My Room")As Lee Wakefield Lacker | (Not seen) |
| movie | The Bridges of Madison County (1995)As Francesca Johnson | (Not seen) |
| movie | The River Wild (1994)As Gail Hartman | (Not seen) |
| movie | The House of the Spirits (1993)As Clara del Valle Trueba | (Not seen) |
| movie | Death Becomes Her (1992)As Madeline Ashton | (Not seen) |
| movie | Defending Your Life (1991)As Julia | (Not seen) |
| movie | Postcards from the Edge (1990)As Suzanne Vale | (Not seen) |
| tv | The Simpsons (1989)As Jessica Lovejoy (voice)(1 episode) | (Not seen) |
| movie | She-Devil (1989)As Mary Fisher | (Not seen) |
| movie | A Cry in the Dark (1988) (AKA "Evil Angels")As Lindy Chamberlain | (Not seen) |
| movie | Ironweed (1987)As Helen Archer | (Not seen) |
| movie | Out of Africa (1985)As Karen Christence Dinesen Blixen | (Not seen) |
| movie | Plenty (1985)As Susan Traherne | (Not seen) |
| movie | Silkwood (1983)As Karen Silkwood | (Not seen) |
| movie | Still of the Night (1982) (AKA "Stab")As Brooke Reynolds | (Not seen) |
| movie | Sophie's Choice (1982)As Zofia "Sophie" Zawistowski | (Not seen) |
| movie | The French Lieutenant's Woman (1981)As Sarah / Anna | (Not seen) |
| movie | Kramer vs. Kramer (1979)As Joanna Kramer | (Not seen) |
| movie | Manhattan (1979)As Jill | (Not seen) |
| movie | The Deer Hunter (1978) (AKA "The Man Who Came to Play")As Linda | (Not seen) |
| movie | Julia (1977)As Anne Marie | (Not seen) |
| tv | Saturday Night Live (1975)As Self(1 episode) | (Not seen) |
| tv | The Oscars (1953)As Self(6 episodes) | (Not seen) |