| movie | The Parenting (2025)As Liddy | (Not seen) |
| tv | Time Bandits (2024)As Penelope(10 episodes) | (Not seen) |
| movie | Friends: The Reunion (2021)As Self | (Not seen) |
| movie | The Boss Baby: Family Business (2021)As Janice Templeton (voice) | (Not seen) |
| tv | Feel Good (2020)As Linda(7 episodes) | (Not seen) |
| tv | Space Force (2020)As Maggie Naird(8 episodes) | (Not seen) |
| movie | Death to 2020 (2020)As Jeanetta Grace Susan | (Not seen) |
| movie | Booksmart (2019)As Charmaine | (Not seen) |
| movie | Long Shot (2019)As Katherine | (Not seen) |
| movie | Table 19 (2017)As Bina Kepp | (Not seen) |
| movie | The Boss Baby (2017)As Janice Templeton (voice) | (Not seen) |
| tv | Angie Tribeca (2016)As Monica Vivarquor(1 episode) | (Not seen) |
| tv | The Good Place (2016)As Hypatia(1 episode) | (Not seen) |
| movie | Americano (2016)As Lucille (voice) | (Not seen) |
| movie | The Girl on the Train (2016)As Martha | (Not seen) |
| movie | Neighbors 2: Sorority Rising (2016) (AKA "Bad Neighbours 2")As Carol Gladstone | (Not seen) |
| tv | The Late Late Show with James Corden (2015)As Self(2 episodes) | (Not seen) |
| tv | The Late Show with Stephen Colbert (2015)As Self(1 episode) | (Not seen) |
| tv | Unbreakable Kimmy Schmidt (2015)As Fairy Godmother (voice)(3 episodes) | (Not seen) |
| tv | BoJack Horseman (2014)As Wanda Pierce (voice)(7 episodes) | (Not seen) |
| tv | The Tonight Show Starring Jimmy Fallon (2014)As Self - Guest(1 episode) | (Not seen) |
| tv | Variety Studio: Actors on Actors (2014)As Self(2 episodes) | (Not seen) |
| tv | Late Night with Seth Meyers (2014)As Self(1 episode) | (Not seen) |
| movie | Neighbors (2014) (AKA "Bad Neighbours")As Carol Gladstone | (Not seen) |
| tv | Rick and Morty (2013)As Tyrannosaurus Rex (voice)(1 episode) | (Not seen) |
| tv | Scandal (2012)As Congresswoman Josephine Marcus(4 episodes) | (Not seen) |
| movie | Pearl Jam Twenty (2011) | (Not seen) |
| movie | Easy A (2010)As Mrs. Griffith | (Not seen) |
| tv | RuPaul's Drag Race (2009)As Self - Special Guest(1 episode) | (Not seen) |
| tv | Cougar Town (2009)As Dr. Amy Evans(1 episode) | (Not seen) |
| movie | The Other Woman (2009)As Carolyne Soule | (Not seen) |
| movie | Paper Man (2009)As Claire Dunn | (Not seen) |
| movie | Hotel for Dogs (2009)As Lois Scudder | (Not seen) |
| movie | Bandslam (2009)As Karen Burton | (Not seen) |
| movie | Powder Blue (2009)As Sally | (Not seen) |
| movie | P.S. I Love You (2007)As Denise | (Not seen) |
| movie | Happy Endings (2005)As Mamie | (Not seen) |
| tv | Real Time with Bill Maher (2003)As Self(1 episode) | (Not seen) |
| movie | Marci X (2003)As Marci Feld | (Not seen) |
| movie | Wonderland (2003) (AKA "The Wonderland Murders")As Sharon Holmes | (Not seen) |
| tv | American Idol (2002)As Self(1 episode) | (Not seen) |
| movie | Analyze That (2002) (AKA "Analyze You")As Laura Sobel | (Not seen) |
| movie | All Over the Guy (2001)As Marie | (Not seen) |
| movie | Dr. Dolittle 2 (2001) (AKA "DR.2")As Ava (voice) | (Not seen) |
| movie | Hanging Up (2000)As Maddy Mozell | (Not seen) |
| movie | Lucky Numbers (2000)As Crystal | (Not seen) |
| movie | Analyze This (1999) (AKA "Analyze Me")As Laura MacNamara Sobel | (Not seen) |
| movie | The Opposite of Sex (1998)As Lucia DeLury | (Not seen) |
| tv | King of the Hill (1997)As Amy Pittman (voice)(1 episode) | (Not seen) |
| movie | Romy and Michele's High School Reunion (1997)As Michele Weinberger | (Not seen) |
| tv | Friends (1994)As Phoebe Buffay(228 episodes) | (Not seen) |
| tv | The Simpsons (1989)As Alex Whitney (voice)(1 episode) | (Not seen) |
| tv | Saturday Night Live (1975)As Self - Host(2 episodes) | (Not seen) |
| tv | The Oscars (1953)As Self(1 episode) | (Not seen) |