| tv | A Man on the Inside (2024)As Charles Nieuwendyk(16 episodes) | (Not seen) |
| tv | Mr. Mayor (2021)As Mayor Neil Bremer(19 episodes) | (Not seen) |
| tv | The Orville (2017)As Admiral Perry(6 episodes) | (Not seen) |
| tv | The Good Place (2016)As Michael(50 episodes) | (Not seen) |
| tv | The Late Show with Stephen Colbert (2015)As Self - Guest(1 episode) | (Not seen) |
| tv | Fargo (2014)As Sheriff Hank Larsson(10 episodes) | (Not seen) |
| tv | Late Night with Seth Meyers (2014)As Self - Guest(5 episodes) | (Not seen) |
| movie | The One I Love (2014)As Therapist | (Not seen) |
| tv | Cuckoo (2012)As Jack Holden (archive footage) | (Not seen) |
| movie | Ted (2012)As Ted Danson (uncredited) | (Not seen) |
| movie | Beastie Boys: Fight for Your Right Revisited (2011) (AKA "Fight for Your Right Revisited")As Maitre D' | (Not seen) |
| tv | Bored to Death (2009)As George Christopher(24 episodes) | (Not seen) |
| tv | Generation Kill (2008)As Moose | (Not seen) |
| movie | The Human Contract (2008)As E.J Winters | (Not seen) |
| movie | Mad Money (2008)As Don Cardigan | (Not seen) |
| movie | Nobel Son (2007)As Harvey Parrish | (Not seen) |
| movie | Knights of the South Bronx (2005)As Richard | (Not seen) |
| tv | The Ellen DeGeneres Show (2003)As Self(2 episodes) | (Not seen) |
| tv | Curb Your Enthusiasm (2000)As Ted Danson(34 episodes) | (Not seen) |
| movie | Homegrown (1998) (AKA "Wild Smokers")As Gianni Saletzzo | (Not seen) |
| movie | Saving Private Ryan (1998)As Captain Fred Hamill | (Not seen) |
| tv | King of the Hill (1997)As Tom Hammond (voice)(1 episode) | (Not seen) |
| tv | The Daily Show (1996)As Self(2 episodes) | (Not seen) |
| tv | Gulliver's Travels (1996)As Lemuel Gulliver(2 episodes) | (Not seen) |
| movie | Getting Even with Dad (1994)As Raymond 'Ray' Gleason | (Not seen) |
| tv | Frasier (1993)As Sam Malone(1 episode) | (Not seen) |
| movie | Made in America (1993)As Halbert 'Hal' Jackson | (Not seen) |
| movie | Three Men and a Little Lady (1990) (AKA "3 Men and a Little Lady")As Jack Holden | (Not seen) |
| tv | The Simpsons (1989)As Sam Malone (voice)(1 episode) | (Not seen) |
| movie | Dad (1989)As John Tremont | (Not seen) |
| movie | Cousins (1989) (AKA "A Touch of Infidelity")As Larry Kozinski | (Not seen) |
| movie | Three Men and a Baby (1987) (AKA "3 Men and a Baby")As Jack Holden | (Not seen) |
| movie | A Fine Mess (1986) (AKA "Blake Edwards' A Fine Mess")As Spence Holden | (Not seen) |
| movie | Creepshow (1982) (AKA "Cuentos de ultratumba")As Harry Wentworth (segment "Something To Tide You Over") | (Not seen) |
| movie | Body Heat (1981)As Peter Lowenstein | (Not seen) |
| tv | Magnum, P.I. (1980)As Stewart Crane(1 episode) | (Not seen) |
| movie | The Onion Field (1979)As Ian Campbell | (Not seen) |
| tv | Saturday Night Live (1975)As Self - Host(2 episodes) | (Not seen) |