| tv | aka Charlie Sheen (2025)As Self(2 episodes) | (Not seen) |
| movie | Brats (2024)As Self | (Not seen) |
| tv | Batwoman (2019)As Lex Luthor(1 episode) | (Not seen) |
| tv | The Joel McHale Show with Joel McHale (2018)As Eugenio Derbez(1 episode) | (Not seen) |
| tv | Will & Grace (2017)As Jon Cryer(1 episode) | (Not seen) |
| tv | DC's Legends of Tomorrow (2016)As Lex Luthor(1 episode) | (Not seen) |
| tv | Supergirl (2015)As Lex Luthor(20 episodes) | (Not seen) |
| tv | The Late Late Show with James Corden (2015)As Self(1 episode) | (Not seen) |
| tv | The Flash (2014)As Lex Luthor(1 episode) | (Not seen) |
| tv | Late Night with Seth Meyers (2014)As Self - Guest(1 episode) | (Not seen) |
| movie | Hit by Lightning (2014)As Ricky Miller | (Not seen) |
| movie | Ass Backwards (2013)As Dean Morris | (Not seen) |
| tv | Arrow (2012)As Lex Luthor(1 episode) | (Not seen) |
| movie | Due Date (2010)As Alan Harper | (Not seen) |
| movie | Stay Cool (2009)As Javier | (Not seen) |
| movie | Shorts (2009) (AKA "Shorts: The Adventures of the Wishing Rock")As Dad Thompson | (Not seen) |
| movie | Unstable Fables: 3 Pigs & a Baby (2008) (AKA "Unstable Fables: 3 Pigs and a Baby")As Richard Pig (voice) | (Not seen) |
| movie | Tortured (2007)As Brian Mark | (Not seen) |
| tv | Danny Phantom (2004)As Freakshow (voice)(2 episodes) | (Not seen) |
| tv | NCIS (2003)As Cyril Taft(3 episodes) | (Not seen) |
| tv | Two and a Half Men (2003)As Alan Harper(262 episodes) | (Not seen) |
| tv | The Ellen DeGeneres Show (2003)As Self(3 episodes) | (Not seen) |
| tv | Family Guy (1999)As Kevin (voice)(1 episode) | (Not seen) |
| movie | Holy Man (1998)As Barry | (Not seen) |
| tv | The Practice (1997)As Terry Pender(1 episode) | (Not seen) |
| movie | Hot Shots! (1991) (AKA "Hot Shots: An Important Movie!")As Jim 'Wash Out' Pfaffenbach | (Not seen) |
| movie | Superman IV: The Quest for Peace (1987) (AKA "Superman IV")As Lenny | (Not seen) |
| movie | Pretty in Pink (1986)As Philip F. "Duckie" Dale | (Not seen) |