| movie | Netflix Tudum 2025 (2025) | (Not seen) |
| movie | Nasty (2024) (AKA "Nasty: More Than Just Tennis") | (Not seen) |
| movie | PAW Patrol: The Mighty Movie (2023)As Yoga Yvette (voice) | (Not seen) |
| tv | Harry & Meghan (2022)As Self(3 episodes) | (Not seen) |
| movie | Glass Onion (2022) (AKA "Glass Onion: A Knives Out Mystery")As Serena Williams | (Not seen) |
| movie | The Inventor: Out for Blood in Silicon Valley (2019) | (Not seen) |
| movie | Ocean's Eight (2018)As Serena Williams | (Not seen) |
| tv | The Late Show with Stephen Colbert (2015)As Self - Guest(1 episode) | (Not seen) |
| tv | Hot Ones (2015)As Self(1 episode) | (Not seen) |
| movie | 7 Days in Hell (2015)As Serena Williams | (Not seen) |
| movie | Pixels (2015)As Serena Willams | (Not seen) |
| tv | The Tonight Show Starring Jimmy Fallon (2014)As Self - Guest(1 episode) | (Not seen) |
| tv | The Legend of Korra (2012)As Female Sage (voice)(1 episode) | (Not seen) |
| tv | Avatar: The Last Airbender (2005)As Ming (voice)(1 episode) | (Not seen) |
| tv | Project Runway (2004)As Self - Guest Judge(1 episode) | (Not seen) |
| tv | America's Next Top Model (2003)As Self - Guest(1 episode) | (Not seen) |
| tv | The Ellen DeGeneres Show (2003)As Self(3 episodes) | (Not seen) |
| tv | Law & Order: Special Victims Unit (1999)As Chloe Spiers(1 episode) | (Not seen) |
| tv | The Daily Show (1996)As Self(1 episode) | (Not seen) |
| tv | ER (1994)As Alice Watson(1 episode) | (Not seen) |
| tv | The Simpsons (1989)As Serena Williams (voice)(1 episode) | (Not seen) |
| tv | The Oscars (1953)As Self(1 episode) | (Not seen) |