| tv | All's Fair (2025)As Carrington Lane(9 episodes) | (Not seen) |
| tv | Mr. & Mrs. Smith (2024)As Therapist(1 episode) | (Not seen) |
| movie | Hold Your Breath (2024)As Margaret Bellum | (Not seen) |
| tv | The Bear (2022)As Cousin Michelle(2 episodes) | (Not seen) |
| tv | Ratched (2020)As Mildred Ratched(8 episodes) | (Not seen) |
| movie | Run (2020)As Mother / Diane | (Not seen) |
| movie | The Goldfinch (2019)As Xandra | (Not seen) |
| movie | Abominable (2019)As Dr. Zara (voice) | (Not seen) |
| movie | Glass (2019)As Dr. Ellie Staple | (Not seen) |
| movie | Bird Box (2018)As Jessica | (Not seen) |
| movie | Ocean's Eight (2018)As Tammy | (Not seen) |
| tv | FEUD (2017)As Geraldine Page(1 episode) | (Not seen) |
| movie | The Post (2017)As Tony Bradlee | (Not seen) |
| movie | Rebel in the Rye (2017)As Dorothy Olding | (Not seen) |
| tv | American Crime Story (2016)As Linda Tripp(20 episodes) | (Not seen) |
| tv | Chelsea (2016)As Self(1 episode) | (Not seen) |
| tv | The Late Show with Stephen Colbert (2015)As Self - Guest(3 episodes) | (Not seen) |
| movie | The Runner (2015)As Kate Haber | (Not seen) |
| movie | Carol (2015)As Abby Gerhard | (Not seen) |
| tv | The Tonight Show Starring Jimmy Fallon (2014)As Self(4 episodes) | (Not seen) |
| tv | Variety Studio: Actors on Actors (2014)As Self(2 episodes) | (Not seen) |
| tv | Late Night with Seth Meyers (2014)As Self - Guest(5 episodes) | (Not seen) |
| movie | 12 Years a Slave (2013)As Mary Epps | (Not seen) |
| movie | Mud (2012)As Mary Lee | (Not seen) |
| tv | American Horror Story (2011)As Lana Winters(96 episodes) | (Not seen) |
| movie | New Year's Eve (2011)As Grace Schwab | (Not seen) |
| movie | The Spirit (2008) (AKA "Will Eisner's The Spirit")As Ellen Dolan | (Not seen) |
| tv | The Graham Norton Show (2007)As Self(3 episodes) | (Not seen) |
| tv | Studio 60 on the Sunset Strip (2006)As Harriet Hayes(22 episodes) | (Not seen) |
| tv | Grey's Anatomy (2005)As Young Ellis Grey(1 episode) | (Not seen) |
| movie | The Notorious Bettie Page (2005)As Bunny Yeager | (Not seen) |
| movie | Serenity (2005)As Dr. Caron | (Not seen) |
| tv | Deadwood (2004)As Alice Isringhausen(12 episodes) | (Not seen) |
| tv | Desperate Housewives (2004)As Lydia Lindquist(1 episode) | (Not seen) |
| tv | Nip/Tuck (2003)As Agatha Ripp(1 episode) | (Not seen) |
| tv | The Ellen DeGeneres Show (2003)As Self(1 episode) | (Not seen) |
| movie | Down with Love (2003) (AKA "Down with Love - Zum Teufel mit der Liebe!")As Vikki Hiller | (Not seen) |
| movie | Bug (2002)As Eilleen | (Not seen) |
| movie | Path to War (2002)As Luci Baines Johnson | (Not seen) |
| movie | What Women Want (2000)As Annie | (Not seen) |
| tv | Law & Order: Special Victims Unit (1999)As Anne Gillette(1 episode) | (Not seen) |
| tv | Family Guy (1999)As Sarah Paulson / Marcia Clark / Costumed Woman (voice)(1 episode) | (Not seen) |
| movie | Held Up (1999)As Mary | (Not seen) |
| tv | Law & Order (1990)As Maggie Conner(1 episode) | (Not seen) |
| tv | Saturday Night Live (1975)As Self - Cameo (uncredited)(1 episode) | (Not seen) |