| movie | Avengers: Doomsday (2026)As Raven Darkholme / Mystique | (Not seen) |
| tv | Star Trek: Strange New Worlds (2022)As Una Chin-Riley(30 episodes) | (Not seen) |
| movie | Batman: Hush (2019)As Lois Lane (voice) | (Not seen) |
| movie | Reign of the Supermen (2019)As Lois Lane (voice) | (Not seen) |
| movie | Satanic Panic (2019)As Danica Ross | (Not seen) |
| movie | The Death of Superman (2018)As Lois Lane (voice) | (Not seen) |
| tv | Star Trek: Discovery (2017)As Number One(3 episodes) | (Not seen) |
| tv | The Late Late Show with James Corden (2015)As Self(1 episode) | (Not seen) |
| movie | Larry Gaye: Renegade Male Flight Attendant (2015)As Sally the Flightpal | (Not seen) |
| tv | Late Night with Seth Meyers (2014)As Self(1 episode) | (Not seen) |
| movie | Phantom Halo (2014)As Ms. Rose | (Not seen) |
| tv | Key & Peele (2012)As Pirate Captain(1 episode) | (Not seen) |
| movie | Good Deeds (2012) (AKA "Tyler Perry's Good Deeds")As Heidi | (Not seen) |
| tv | NTSF:SD:SUV:: (2011)As Jessie Nichols(27 episodes) | (Not seen) |
| movie | X-Men: First Class (2011) (AKA "X-Men: First Generation")As Mystique - Older | (Not seen) |
| tv | RuPaul's Drag Race (2009)As Self - Guest Judge(1 episode) | (Not seen) |
| tv | Chuck (2007)As Robin Cunnings(1 episode) | (Not seen) |
| movie | Man About Town (2006)As Nina Giamoro | (Not seen) |
| movie | X-Men: The Last Stand (2006) (AKA "X-Men 3")As Raven Darkholme / Mystique | (Not seen) |
| tv | Drawn Together (2004)As Charlotte (voice)(1 episode) | (Not seen) |
| tv | Project Runway (2004)As Self - Guest Judge(1 episode) | (Not seen) |
| movie | The Punisher (2004)As Joan | (Not seen) |
| movie | Godsend (2004) (AKA "Adam")As Jessie Duncan | (Not seen) |
| tv | The Ellen DeGeneres Show (2003)As Self(2 episodes) | (Not seen) |
| movie | X2: X-Men United (2003) (AKA "X-Men 2")As Raven Darkholme / Mystique / Grace | (Not seen) |
| tv | American Idol (2002)As Self(1 episode) | (Not seen) |
| movie | Femme Fatale (2002)As Laure/lily | (Not seen) |
| movie | S1m0ne (2002) (AKA "Simone")As Faith | (Not seen) |
| movie | Rollerball (2002)As Aurora | (Not seen) |
| tv | Curb Your Enthusiasm (2000)As Penelope(1 episode) | (Not seen) |
| movie | X-Men (2000)As Raven Darkholme / Mystique | (Not seen) |
| movie | Austin Powers: The Spy Who Shagged Me (1999) (AKA "Austin Powers 2")As Rebecca Romijn | (Not seen) |
| movie | Dirty Work (1998)As Bearded Lady | (Not seen) |
| tv | The Daily Show (1996)As Self(3 episodes) | (Not seen) |
| tv | Friends (1994)As Cheryl(1 episode) | (Not seen) |
| tv | MTV Video Music Awards (1984)As Self - Preshow Host(1 episode) | (Not seen) |