| movie | The Bride (2026) (AKA "The Bride!")As Myrna | (Not seen) |
| movie | Ferrari (2023)As Laura Ferrari | (Not seen) |
| movie | The 355 (2022)As Graciela Rivera | (Not seen) |
| movie | Parallel Mothers (2021)As Janis | (Not seen) |
| tv | Home Movie: The Princess Bride (2020)As Prince Humperdinck / Princess Buttercup(1 episode) | (Not seen) |
| movie | Pain and Glory (2019)As Jacinta | (Not seen) |
| movie | Loving Pablo (2017)As Virginia Vallejo | (Not seen) |
| movie | Murder on the Orient Express (2017)As Pilar Estravados | (Not seen) |
| tv | American Crime Story (2016)As Donatella Versace(9 episodes) | (Not seen) |
| movie | The Queen of Spain (2016)As Macarena Granada | (Not seen) |
| movie | Zoolander 2 (2016) (AKA "2oolander")As Valentina Valencia | (Not seen) |
| movie | The Brothers Grimsby (2016) (AKA "Brothers Grimsby")As Kate | (Not seen) |
| tv | The Tonight Show Starring Jimmy Fallon (2014)As Self(2 episodes) | (Not seen) |
| tv | Variety Studio: Actors on Actors (2014)As Self(1 episode) | (Not seen) |
| tv | Late Night with Seth Meyers (2014)As Self(1 episode) | (Not seen) |
| movie | The Counselor (2013) (AKA "The Counsellor")As Laura | (Not seen) |
| movie | Twice Born (2012) (AKA "Venuto al mondo")As Gemma | (Not seen) |
| movie | To Rome with Love (2012)As Anna | (Not seen) |
| movie | Pirates of the Caribbean: On Stranger Tides (2011) (AKA "P.O.T.C. 4")As Angélica | (Not seen) |
| movie | Sex and the City 2 (2010)As Carmen García Carrión | (Not seen) |
| movie | G-Force (2009) (AKA "Spy Animal: G-Force")As Juarez the Guinea Pig (voice) | (Not seen) |
| movie | La concejala antropófaga (2009) (AKA "La concejala antropofaga")As Pina | (Not seen) |
| movie | Nine (2009)As Carla | (Not seen) |
| movie | Broken Embraces (2009) (AKA "Los abrazos rotos")As Lena | (Not seen) |
| movie | Vicky Cristina Barcelona (2008)As María Elena | (Not seen) |
| tv | The Graham Norton Show (2007)As Self(2 episodes) | (Not seen) |
| movie | The Good Night (2007)As Anna/Melodia | (Not seen) |
| movie | Bandidas (2006)As Maria Alvarez | (Not seen) |
| movie | Volver (2006) (AKA "To Return")As Raimunda | (Not seen) |
| movie | Chromophobia (2005)As Gloria | (Not seen) |
| movie | Sahara (2005)As Eva Rojas | (Not seen) |
| movie | Head in the Clouds (2004)As Mia | (Not seen) |
| tv | The Ellen DeGeneres Show (2003)As Self(1 episode) | (Not seen) |
| movie | Fanfan (2003) (AKA "Fan-Fan the Tulip")As Adeline La Franchise | (Not seen) |
| movie | Gothika (2003)As Chloe Sava | (Not seen) |
| movie | Captain Corelli's Mandolin (2001)As Pelagia | (Not seen) |
| movie | Blow (2001)As Mirtha Jung | (Not seen) |
| movie | Vanilla Sky (2001)As Sofia Serrano | (Not seen) |
| movie | All the Pretty Horses (2000)As Alejandra | (Not seen) |
| movie | All About My Mother (1999) (AKA "Todo sobre mi madre")As Rosa | (Not seen) |
| movie | Live Flesh (1997)As Isabel Plaza Caballero | (Not seen) |
| movie | Open Your Eyes (1997)As Sofía | (Not seen) |
| movie | Jamón, Jamón (1992) (AKA "A Tale of Ham and Passion")As Silvia | (Not seen) |
| movie | Belle Epoque (1992) (AKA "Belle Époque")As Luz | (Not seen) |
| tv | The Oscars (1953)As Self(4 episodes) | (Not seen) |