| tv | Wonder Man (2026)As Mario Lopez(1 episode) | (Not seen) |
| movie | Zootopia 2 (2025)As Denny Howlett (voice) | (Not seen) |
| movie | Heads of State (2025)As Mario Lopez | (Not seen) |
| tv | Loot (2022)As Mario Lopez(1 episode) | (Not seen) |
| tv | Girls5eva (2021)As Mario López(1 episode) | (Not seen) |
| tv | Hacks (2021)As Mario López(1 episode) | (Not seen) |
| movie | Kid 90 (2021)As Self (archive footage) | (Not seen) |
| tv | Saved by the Bell (2020)As A.C. Slater(20 episodes) | (Not seen) |
| tv | Too Hot to Handle (2020)As Self(1 episode) | (Not seen) |
| tv | The Other Two (2019)As Mario López(1 episode) | (Not seen) |
| tv | Magnum P.I. (2018)As Mario Lopez(1 episode) | (Not seen) |
| tv | The Rookie (2018)As Mario López(1 episode) | (Not seen) |
| tv | This Is Us (2016)As Mario López(2 episodes) | (Not seen) |
| movie | Grease Live! (2016) (AKA "Grease Live")As Vince Fontaine | (Not seen) |
| movie | Popstar: Never Stop Never Stopping (2016)As Mario López | (Not seen) |
| tv | Rosewood (2015)As Mario López(1 episode) | (Not seen) |
| tv | Jane the Virgin (2014)As Himself(1 episode) | (Not seen) |
| tv | The Tonight Show Starring Jimmy Fallon (2014)As Self(1 episode) | (Not seen) |
| movie | Hits (2014)As Extra Host | (Not seen) |
| tv | Man Down (2013)As Zeus (voice) | (Not seen) |
| tv | Brooklyn Nine-Nine (2013)As Mario Lopez(1 episode) | (Not seen) |
| movie | The Smurfs 2 (2013)As Social Smurf (voice) | (Not seen) |
| movie | Step Up: Revolution (2012) (AKA "Step Up Revolution")As Mario Lopez (uncredited) | (Not seen) |
| movie | Get Him to the Greek (2010) (AKA "American Trip")As Self | (Not seen) |
| tv | Nip/Tuck (2003)As Dr. Mike Hamoui(8 episodes) | (Not seen) |
| tv | America's Next Top Model (2003)As Self - Guest(1 episode) | (Not seen) |
| tv | The Ellen DeGeneres Show (2003)As Self(2 episodes) | (Not seen) |
| movie | Pauly Shore Is Dead (2003)As Self | (Not seen) |
| movie | A Crack in the Floor (2001)As Lehman | (Not seen) |
| tv | Family Guy (1999)As Mario Lopez (voice)(1 episode) | (Not seen) |
| movie | Killing Mr. Griffin (1997)As Dave Ruggles | (Not seen) |
| movie | Saved by the Bell: Wedding in Las Vegas (1994)As A.C. Slater | (Not seen) |
| movie | Saved by the Bell: Hawaiian Style (1992)As A.C. Slater | (Not seen) |
| movie | Colors (1988)As felipe's friend | (Not seen) |