| tv | aka Charlie Sheen (2025)As Self (archive footage)(2 episodes) | (Not seen) |
| movie | Brats (2024) | (Not seen) |
| movie | 12 Mighty Orphans (2021)As Doc Hall | (Not seen) |
| movie | Judas and the Black Messiah (2021)As J. Edgar Hoover | (Not seen) |
| movie | A West Wing Special to Benefit When We All Vote (2020)As President Josiah Bartlet | (Not seen) |
| movie | The Devil Has a Name (2019)As Ralph | (Not seen) |
| movie | Come Sunday (2018)As Oral Roberts | (Not seen) |
| movie | Popstar: Never Stop Never Stopping (2016)As Martin Sheen | (Not seen) |
| tv | Last Week Tonight with John Oliver (2014)As Self(1 episode) | (Not seen) |
| movie | Selma (2014)As Frank Minis Johnson (uncredited) | (Not seen) |
| movie | Trash (2014)As Father Juilliard / Padre Juilliard | (Not seen) |
| movie | Ask Me Anything (2014) | (Not seen) |
| movie | The Amazing Spider-Man 2 (2014) (AKA "The Amazing Spider-Man 2: Rise of Electro")As Uncle Ben (uncredited) | (Not seen) |
| movie | The Amazing Spider-Man (2012) (AKA "The Amazing Spider-Man in 3D")As Uncle Ben | (Not seen) |
| movie | Seeking a Friend for the End of the World (2012)As Frank Petersen | (Not seen) |
| movie | The Double (2011)As Tom Highland | (Not seen) |
| movie | The Way (2010)As Tom | (Not seen) |
| movie | Imagine That (2009)As Dante D'Enzo | (Not seen) |
| movie | Love Happens (2009) (AKA "Brand New Day")As Burke's Father-in-Law | (Not seen) |
| movie | Echelon Conspiracy (2009) (AKA "The Gift")As Raymond Burke | (Not seen) |
| tv | Diners, Drive-Ins and Dives (2007)As Self(1 episode) | (Not seen) |
| tv | The Graham Norton Show (2007)As Self(1 episode) | (Not seen) |
| tv | Studio 60 on the Sunset Strip (2006)As Radio Host(1 episode) | (Not seen) |
| movie | Bobby (2006)As Jack Stevens | (Not seen) |
| movie | The Departed (2006) (AKA "Infernal Affairs")As Capt. Oliver Charles Queenan | (Not seen) |
| movie | The Nomi Song (2004)As Self (archive footage) | (Not seen) |
| tv | Two and a Half Men (2003)As Harvey(1 episode) | (Not seen) |
| tv | The Ellen DeGeneres Show (2003)As Self - Guest(4 episodes) | (Not seen) |
| movie | "Comedy Central Roasts" Comedy Central Roast of Denis Leary (2003) (AKA "Comedy Central Roast of Denis Leary") | (Not seen) |
| movie | All the Presidents' Movies (2003) | (Not seen) |
| movie | Bringing Down a Dictator (2002)As Narrator (voice) | (Not seen) |
| movie | Catch Me If You Can (2002)As Roger Strong | (Not seen) |
| movie | O (2001) (AKA "Othello")As Coach Duke Goulding | (Not seen) |
| tv | The West Wing (1999)As Josiah Bartlet(154 episodes) | (Not seen) |
| movie | A Texas Funeral (1999)As Grandpa Sparta | (Not seen) |
| movie | Thrill Seekers (1999) (AKA "The Time Shifters")As Grifasi | (Not seen) |
| movie | No Code of Conduct (1998) (AKA "The Last Child")As Bill Peterson | (Not seen) |
| movie | Medusa's Child (1997)As President | (Not seen) |
| movie | Spawn (1997)As Jason Wynn | (Not seen) |
| movie | Truth or Consequences, N.M. (1997)As Sir | (Not seen) |
| movie | Project: ALF (1996)As Colonel Gilbert Milfoil | (Not seen) |
| movie | Dead Presidents (1995)As The Judge | (Not seen) |
| movie | The American President (1995) (AKA "Perfect Couple")As A.J. MacInerney | (Not seen) |
| movie | Hot Shots! Part Deux (1993) (AKA "Hot Shots 2! The Exploitation")As Capt. Benjamin L. Willard (uncredited) | (Not seen) |
| movie | Hearts of Darkness: A Filmmaker's Apocalypse (1991)As Self | (Not seen) |
| movie | JFK (1991)As Narrator (voice) (uncredited) | (Not seen) |
| movie | Cadence (1990)As MSgt. Otis V. McKinney | (Not seen) |
| tv | The Simpsons (1989)As Real Seymour Skinner (voice)(1 episode) | (Not seen) |
| movie | Beastie Boys: Shadrach (1989) (AKA "Shadrach")As Narrator (voice) | (Not seen) |
| movie | Judgment in Berlin (1988)As Herbert J. Stern | (Not seen) |
| movie | Siesta (1987)As Del | (Not seen) |
| movie | The Believers (1987)As Cal Jamison | (Not seen) |
| movie | Wall Street (1987)As Carl Fox | (Not seen) |
| movie | Firestarter (1984)As Captain Hollister | (Not seen) |
| movie | The Dead Zone (1983)As Greg Stillson | (Not seen) |
| movie | Gandhi (1982) (AKA "Richard Attenborough's Film: Gandhi")As Vince Walker | (Not seen) |
| movie | The Final Countdown (1980)As Warren Lasky | (Not seen) |
| movie | Apocalypse Now (1979) (AKA "Apocalypse Now Redux")As Captain Benjamin L. Willard | (Not seen) |
| movie | The Little Girl Who Lives Down the Lane (1976)As Frank Hallet | (Not seen) |
| movie | The Cassandra Crossing (1976) (AKA "Cassandra Crossing")As Robby Navarro | (Not seen) |
| tv | Saturday Night Live (1975)As Self - Cameo (uncredited)(2 episodes) | (Not seen) |
| movie | Badlands (1973)As Kit Carruthers | (Not seen) |
| movie | Catch-22 (1970)As 1st Lt. Dobbs | (Not seen) |
| tv | Flipper (1964)As Phil Adams(1 episode) | (Not seen) |